KRT13 polyclonal antibody
产品名称： KRT13 polyclonal antibody
英文名称： KRT13 polyclonal antibody
产品编号： PAB11444
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of KRT13.
- Immunogen:
- A synthetic peptide corresponding to human KRT13.
- Sequence:
- C-TSNASGRRTSDVRRP
- Host:
- Goat
- Theoretical MW (kDa):
- 49.6, 45.8
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation.
Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM.J Biol Chem. 2007 Aug 24;282(34):24858-65. Epub 2007 Jun 27.
- Applications
- Western Blot (Tissue lysate)
- KRT13 polyclonal antibody (Cat # PAB11444) (0.1 ug/mL) staining of human lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 3860
- Protein Accession#:
- NP_705694.2
- Gene Name:
- KRT13
- Gene Alias:
- CK13,K13,MGC161462,MGC3781
- Gene Description:
- keratin 13
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq
- Other Designations:
- cytokeratin 13,keratin, type I cytoskeletal 13