ENG monoclonal antibody (M01), clone 4C11
产品名称： ENG monoclonal antibody (M01), clone 4C11
英文名称： ENG monoclonal antibody (M01), clone 4C11
产品编号： H00002022-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant ENG.
- Immunogen:
- ENG (AAH14271, 27 a.a. ~ 658 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TVHCDLQPVGPERDEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (95.26 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of ENG expression in transfected 293T cell line by ENG monoclonal antibody (M01), clone 4C11.
Lane 1: ENG transfected lysate(70.6 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of ENG transfected lysate using anti-ENG monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with ENG MaxPab rabbit polyclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ENG is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 2022
- GeneBank Accession#:
- BC014271
- Protein Accession#:
- AAH14271
- Gene Name:
- ENG
- Gene Alias:
- CD105,END,FLJ41744,HHT1,ORW,ORW1
- Gene Description:
- endoglin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD105 antigen,OTTHUMP00000022221,Osler-Rendu-Weber syndrome 1
- Related Disease
- Aneurysm
- Aneurysm, Ruptured
- Arteriovenous Malformations
- Cardiovascular Diseases
- Central Nervous System Vascular Malformations
- Chromosome Aberrations
- Diabetes Mellitus, Type 2
- Edema
- Epistaxis
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Hypertension, Pulmonary
- Intracranial Aneurysm
- Intracranial Arteriovenous Malformations
- Kidney Failure, Chronic
- Liver Cirrhosis
- Liver Diseases
- Lung Neoplasms
- Pre-Eclampsia